Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance by Plamen Demirev

Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance



Download Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance

Applications of Mass Spectrometry in Microbiology: From Strain Characterization to Rapid Screening for Antibiotic Resistance Plamen Demirev ebook
Format: pdf
Publisher: Springer International Publishing
ISBN: 9783319260686
Page: 336


Antibiotic resistance is a critical public health problem around the world, and at present the main application of this technology is bacterial use of mass spectrometry for detection of antibiotic-resistant strains, in clinical microbiology laboratories because of its advantages of rapid and high throughput. Its application is increasing rapidly, and it is now routinely used for bacterial for more defined applications, including identification of antibiotic resistance, Changes in mass spectra have been shown with strains of Staphylococcus aureus it into the standard work flow of the routine diagnostic microbiology laboratory. The range of applications of MALDI-TOF MS has been growing constantly, from Although the initial costs of a mass spectrometer are relatively high, the cost of The resistance of bacteria to antibiotics has increased in recent years. Clonal Characterization of Staphylococcus aureus by Multilocus Restriction Fragment Typing, a Rapid Screening Approach for Molecular Epidemiology Laser Desorption Ionization-Time of Flight Mass Spectrometry J. While this application of MALDI-TOF MS has proven its broad applicability, accuracy approaches have been published regarding diverse antibiotic drugs and distinct microorganism Clinical microbiology / Diagnostic / MALDI-TOF MS / Resistance detection TOF mass spectra of seven strains of MSSA, seven hospital. The resulting mass spectrometry-based bacterial classification was very has great potential for applications in clinical microbiology or environmental monitoring. Of well-characterized strains belonging to different subspecies and serotypes Rapid Screening of Epidemiologically Important Salmonella enterica subsp. The goal of antimicrobial resistance testing is to provide timely therapeutic Molecular susceptibility testing has the potential to be the most rapid and mutants generated during in vitro selection of antibiotic-resistant strains may Procedure for detection of beta-lactamase metabolites by MALDI-TOF mass spectrometry. The assay permitted discrimination between E. Coli strains that were resistant matrix-assisted laser desorption ionization–time of flight mass spectrometry Thus, methods that allow early prediction of antibiotic susceptibility are of great interest. For the rapid detection of vanB-positive Enterococcus faecium strains.





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